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AKA-49
Ertugliflozin
Cat. No.
AKA-49
CAS No.
1210344-57-2
MF
C22H25ClO7
MW
436.9
Ertugliflozin is a potent, selective and active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).
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Technical Data
Description
Storage and Shipping
References
Product Name
Ertugliflozin
CAS No.
1210344-57-2
MF
C22H25ClO7
MW
436.9
Specification
98%
Description
Ertugliflozin is a potent, selective and active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2). Packing: 1kg/bag; 25kg/drum or as request Availability: In Stock
Documents
Certificate of Analysis (COA), API specification, Safety Data Sheet (SDS/MSDS), evidence of GMP compliance, Stability data / Stability summary, etc.
Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Mascitti V, et al. Discovery of a clinical candidate from the structurally unique dioxa-bicyclo[3.2.1]octane class of sodium-dependent glucose cotransporter 2 inhibitors. Journal of Medicinal Chemistry. 2011 Apr 28;54(8):2952-60. PMID: 21449606
[2]. Miao Z, et al. Pharmacokinetics, metabolism, and excretion of the antidiabetic agent ertugliflozin (PF-04971729) in healthy male subjects. Drug Metabolism and Disposition. 2013 Feb;41(2):445-56. PMID: 23169609
[3]. Kalgutkar AS, et al. Preclinical species and human disposition of PF-04971729, a selective inhibitor of the sodium-dependent glucose cotransporter 2 and clinical candidate for the treatment of type 2 diabetes mellitus. Drug Metabolism and Disposition. 2011 Sep;39(9):1609-19. PMID: 21690265
[2]. Miao Z, et al. Pharmacokinetics, metabolism, and excretion of the antidiabetic agent ertugliflozin (PF-04971729) in healthy male subjects. Drug Metabolism and Disposition. 2013 Feb;41(2):445-56. PMID: 23169609
[3]. Kalgutkar AS, et al. Preclinical species and human disposition of PF-04971729, a selective inhibitor of the sodium-dependent glucose cotransporter 2 and clinical candidate for the treatment of type 2 diabetes mellitus. Drug Metabolism and Disposition. 2011 Sep;39(9):1609-19. PMID: 21690265
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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