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AKA-383
Brivaracetam
Cat. No.
AKA-383
CAS No.
357336-20-0
MF
C11H20N2O2
MW
212.29
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Technical Data
Description
Documents
Storage and Shipping
References
Product Name
Brivaracetam
CAS No.
357336-20-0
MF
C11H20N2O2
MW
212.29
Specification
97.0%~102.0%
Description
Brivaracetam is a pyrrolidone derivative that exhibits high affinity and selectivity for synaptic vesicle protein 2A (SV2A). It exerts its antiepileptic effects by modulating processes involved in synaptic neurotransmitter release. Packing: 1kg/bag，5kg/bag，10kg/bag Availability: In stock API Current Development Status: A3---Process Development / Scale-Up Reference: Aktin major API development processes: A1.Feasibility / Route Development A2.Laboratory Process Development A3.Process Development / Scale-Up A4.GMP Clinical Development A5.Commercial GMP Supply
Documents
-
Specification sheet
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Certificate of Analysis (COA), API specification, Safety Data Sheet (SDS/MSDS), evidence of GMP compliance, Stability data / Stability summary, etc.
Storage and Shipping
Store in a cool and dry place, avoid strong light and high temperature.
References
[1].Gayke M, Narode H, Eppa G, Bhosale RS, Yadav JS. Synthetic approaches toward the synthesis of brivaracetam: an antiepileptic drug. ACS Omega. 2022;7(3):2486-2503. doi:10.1021/acsomega.1c05378
[2].Qiu S, Tehrani KA, Sergeyev S, Bultinck P, Herrebout W, Mathieu B. Stereochemistry of the brivaracetam diastereoisomers. Chirality. 2016;28(3):215-225. doi:10.1002/chir.22558
[3].Matagne A, Margineanu DG, Kenda B, Michel P, Klitgaard H. Anti-convulsive and anti-epileptic properties of brivaracetam (ucb 34714), a high-affinity ligand for the synaptic vesicle protein, SV2A. Br J Pharmacol. 2008;154(8):1662-1671. doi:10.1038/bjp.2008.198
[4].Gillard M, Fuks B, Leclercq K, Matagne A. Binding characteristics of brivaracetam, a selective, high affinity SV2A ligand in rat, mouse and human brain: relationship to anti-convulsant properties. Eur J Pharmacol. 2011;664(1-3):36-44. doi:10.1016/j.ejphar.2011.04.064
Disclaimer
The information provided on generic APIs is for general reference and market assessment purposes only. Regulatory status, market availability, specifications, patents, and commercial terms may vary by country and change over time. Users should independently verify all information with the relevant regulatory authorities and qualified professionals before making any regulatory, manufacturing, investment, or commercial decisions. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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