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AKA-386
Polymyxin B Sulfate
Cat. No.
AKA-386
CAS No.
1405-20-5
MF
C56H98N16O13（Free Base）
MW
1203.48（Free Base）
Polymyxin B Sulfate is a cyclic polypeptide antibiotic belonging to the polymyxin class.
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Technical Data
Description
Documents
Storage and Shipping
References
Product Name
Polymyxin B Sulfate
CAS No.
1405-20-5
MF
C56H98N16O13（Free Base）
MW
1203.48（Free Base）
Specification
USP Grade
Research area
Antibacterial / Antimicrobial
Description
Polymyxin B Sulfate is a cyclic polypeptide antibiotic belonging to the polymyxin class. Packing: 1g/bottle, 5g/bottle, 10g/bottle，25g/bottle，100g/bottle Availability: In stock API Current Development Status: A3---Process Development / Scale-Up Reference: Aktin major API development processes: A1.Feasibility / Route Development A2.Laboratory Process Development A3.Process Development / Scale-Up A4.GMP Clinical Development A5.Commercial GMP Supply
Documents
-
Specification sheet
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Certificate of Analysis (COA), API specification sheet, Safety Data Sheet (SDS/MSDS), evidence of GMP compliance, Stability data / Stability summary, etc.
Storage and Shipping
Store under frozen or refrigerated conditions, keep away from strong light and heat.
References
[1].Choi SK, Park SY, Kim R, Lee CH, Kim JF, Park SH. Identification of a polymyxin synthetase gene cluster of Paenibacillus polymyxa and heterologous expression of the gene cluster in Bacillus subtilis. J Bacteriol. 2009;191(10):3350-3358. doi: 10.1128/JB.01728-08
[2].Orwa JA, Govaerts C, Busson R, Roets E, Van Schepdael A, Hoogmartens J. Isolation and structural characterization of polymyxin B components. J Chromatogr A. 2001;912(2):369-373. doi: 10.1016/S0021-9673(01)00585-4
[3].Roberts KD, Azad MAK, Wang J, Horne AS, Thompson PE, Nation RL, et al. Antimicrobial activity and toxicity of the major lipopeptide components of polymyxin B and colistin: last-line antibiotics against multidrug-resistant Gram-negative bacteria. ACS Infect Dis. 2015;1(11):568-575. doi: 10.1021/acsinfecdis.5b00085
[4].Suzuki T, Hayashi K, Fujikawa K, Tsukamoto K. Contribution to the elucidation of the chemical structure of polymyxin B1. J Biochem. 1964;56(4):335-343. doi: 10.1093/oxfordjournals.jbchem.a127998
Disclaimer
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