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AKA-197
Lenacapavir Sodium
Cat. No.
AKA-197
CAS No.
2283356-12-5
MF
C39H32ClF10N7O5S2.Na
MW
991.28
Lenacapavir sodium is a first-in-class capsid protein inhibitor that binds at the interface between capsid hexamers and CA monomers, disrupting capsid assembly and viral maturation.
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Technical Data
Description
Storage and Shipping
References
Product Name
Lenacapavir Sodium
CAS No.
2283356-12-5
MF
C39H32ClF10N7O5S2.Na
MW
991.28
Specification
98%
Research Area
Anti-HIV
Description
Lenacapavir sodium is a first-in-class capsid protein inhibitor that binds at the interface between capsid hexamers and CA monomers, disrupting capsid assembly and viral maturation. Packing: 1kg/bag; 25kg/drum or as request Availability: API for research only, commercial supply only after the patent expires
Documents
Certificate of Analysis (COA), API specification, Safety Data Sheet (SDS/MSDS), evidence of GMP compliance, Stability data / Stability summary, etc.
Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. De Clercq E, et al. Lenacapavir: A capsid inhibitor for HIV-1 treatment and prevention. Biochemical Pharmacology. 2025 Oct;240:117125.
[2]. Link JO, et al. Clinical targeting of HIV-1 capsid protein with a long-acting small molecule. Nature. 2020;584(7822):614-618.
[3]. Singh K, et al. GS-CA Compounds: First-In-Class HIV-1 Capsid Inhibitors Covering Multiple Grounds. Front Microbiol. 2019;10:1227.
[2]. Link JO, et al. Clinical targeting of HIV-1 capsid protein with a long-acting small molecule. Nature. 2020;584(7822):614-618.
[3]. Singh K, et al. GS-CA Compounds: First-In-Class HIV-1 Capsid Inhibitors Covering Multiple Grounds. Front Microbiol. 2019;10:1227.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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