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AKA-197
Lenacapavir Sodium
Cat. No.
AKA-197
CAS No.
2283356-12-5
MF
C39H32ClF10N7O5S2.Na
MW
991.28
Lenacapavir sodium is a first-in-class capsid protein inhibitor that binds at the interface between capsid hexamers and CA monomers, disrupting capsid assembly and viral maturation.
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Description
Storage and Shipping
References
Product Name
Lenacapavir Sodium
CAS No.
2283356-12-5
MF
C39H32ClF10N7O5S2.Na
MW
991.28
Specification
98%
Research Area
Anti-HIV
Description
Lenacapavir sodium is a first-in-class capsid protein inhibitor that binds at the interface between capsid hexamers and CA monomers, disrupting capsid assembly and viral maturation. Packing: 1kg/bag; 25kg/drum or as request Availability: API for research only, commercial supply only after the patent expires
Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. De Clercq E, et al. Lenacapavir: A capsid inhibitor for HIV-1 treatment and prevention. Biochemical Pharmacology. 2025 Oct;240:117125.
[2]. Link JO, et al. Clinical targeting of HIV-1 capsid protein with a long-acting small molecule. Nature. 2020;584(7822):614-618.
[3]. Singh K, et al. GS-CA Compounds: First-In-Class HIV-1 Capsid Inhibitors Covering Multiple Grounds. Front Microbiol. 2019;10:1227.
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