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AKA-185
Tauroursodeoxycholic Acid
Cat. No.
AKA-185
CAS No.
14605-22-2
MF
C26H45NO6S
MW
499.71
Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an active endoplasmic reticulum (ER) stress inhibitor that also inhibits ERK and reduces caspase-3/caspase-12 expression.
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References
Product Name
Tauroursodeoxycholic Acid
CAS No.
14605-22-2
MF
C26H45NO6S
MW
499.71
Specification
98%
Research Area
Primary biliary cholangitis and specific cholestatic liver diseases
Description
Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an active endoplasmic reticulum (ER) stress inhibitor that also inhibits ERK and reduces caspase-3/caspase-12 expression. Packing: 1kg/bag; 25kg/drum or as request Availability: In stock
Documents
Certificate of Analysis (COA), API specification, Safety Data Sheet (SDS/MSDS), evidence of GMP compliance, Stability data / Stability summary, etc.
Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Kim SY, et al. Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK via PKCα-mediated MKP-1 induction. Cardiovascular Research. 2011 Nov 1;92(2):307-16.
[2]. Qin Y, et al. Tauroursodeoxycholic Acid Attenuates Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-deficient Mice by Inhibiting Endoplasmic Reticulum Stress. European Journal of Vascular and Endovascular Surgery. 2017 Mar;53(3):337-345.
[2]. Qin Y, et al. Tauroursodeoxycholic Acid Attenuates Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-deficient Mice by Inhibiting Endoplasmic Reticulum Stress. European Journal of Vascular and Endovascular Surgery. 2017 Mar;53(3):337-345.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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