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AKA-02
Tizanidine Hydrochloride
Cat. No.
AKA-02
CAS No.
64461-82-1
MF
C9H9Cl2N5S
MW
290.17
Tizanidine Hydrochloride is an α2‑adrenergic receptor agonist that inhibits the release of neurotransmitters from CNS norepinephrine‑activated neurons.
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Technical Data
Description
Storage and Shipping
References
Product Name
Tizanidine Hydrochloride
CAS No.
64461-82-1
MF
C9H9Cl2N5S
MW
290.17
Specification
USP/EP/CP
Research Area
Muscle Relaxant
Description
Tizanidine Hydrochloride is an α2‑adrenergic receptor agonist that inhibits the release of neurotransmitters from CNS norepinephrine‑activated neurons. Packing: 1kg/bag; 25kg/drum or as request Availability: In stock
Documents
Certificate of Analysis (COA), API specification, Safety Data Sheet (SDS/MSDS), evidence of GMP compliance, Stability data / Stability summary, etc.
Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Kamen L, et al. A practical overview of tizanidine use for spasticity secondary to multiple sclerosis, stroke, and spinal cord injury. Current Medical Research and Opinion. 2008 Feb;24(2):425-39.
[2]. Granfors MT, Backman JT, Laitila J, Neuvonen PJ. Tizanidine is mainly metabolized by cytochrome p450 1A2 in vitro. British Journal of Clinical Pharmacology. 2004 Mar;57(3):349-53. doi: 10.1046/j.1365-2125.2003.02028.x. PMID: 14998432; PMCID: PMC1884447.
[3]. Zhao L, Zhao G, Xue Q. Tizanidine (Hydrochloride) Inhibits A549 Lung Cancer Cell Proliferation and Motility Through Regulating Nischarin. OncoTargets and Therapy. 2020 Jan 10;13:291-298.
[4]. Rodríguez-Palma EJ, et al. Sex-dependent antiallodynic effect of α2 adrenergic receptor agonist tizanidine in rats with experimental neuropathic pain. European Journal of Pharmacology. 2022 Apr 5;920:174855.
[2]. Granfors MT, Backman JT, Laitila J, Neuvonen PJ. Tizanidine is mainly metabolized by cytochrome p450 1A2 in vitro. British Journal of Clinical Pharmacology. 2004 Mar;57(3):349-53. doi: 10.1046/j.1365-2125.2003.02028.x. PMID: 14998432; PMCID: PMC1884447.
[3]. Zhao L, Zhao G, Xue Q. Tizanidine (Hydrochloride) Inhibits A549 Lung Cancer Cell Proliferation and Motility Through Regulating Nischarin. OncoTargets and Therapy. 2020 Jan 10;13:291-298.
[4]. Rodríguez-Palma EJ, et al. Sex-dependent antiallodynic effect of α2 adrenergic receptor agonist tizanidine in rats with experimental neuropathic pain. European Journal of Pharmacology. 2022 Apr 5;920:174855.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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