Adenine
Cat. No.
AKA-01
CAS No.
73-24-5
MF
C5H5N5
MW
135.1267
Adenine is a purine, one of the four nucleobases in the nucleic acid of DNA.
Tizanidine Hydrochloride
Cat. No.
AKA-02
CAS No.
64461-82-1
MF
C9H9Cl2N5S
MW
290.17
Tizanidine Hydrochloride is an α2‑adrenergic receptor agonist that inhibits the release of neurotransmitters from CNS norepinephrine‑activated neurons.
N-Acetyltizanidine
Cat. No.
AKA-03
CAS No.
173532-15-5
MF
C11H10ClN5OS
MW
295.748
N-Acetyltizanidine is the N-acetylated derivative of tizanidine and is designated as Tizanidine USP Related Compound B.
1-Acetyl-2-imidazolidinone
Cat. No.
AKA-04
CAS No.
5391-39-9
MF
C5H8N2O2
MW
128.131
1-Acetyl-2-imidazolidinone is an imidazolidinone pharmaceutical intermediate. It is designated as Clonidine EP Impurity A and serves as a reference standard for clonidine hydrochloride impurity profiling.
Traxoprodil
Cat. No.
AKA-05
CAS No.
134234-12-1
MF
C20H25NO3
MW
327.4174
Traxoprodil is a potent and selective NMDA NR2B antagonist.
(1E,4E)-1,5-Bis(2-methoxyphenyl)penta-1,4-dien-3-one
Cat. No.
AKA-06
CAS No.
39777-61-2
MF
C19H18O3
MW
294.35
(1E,4E)-1,5-Bis(2-methoxyphenyl)penta-1,4-dien-3-one, also known as TFEB Activator 1 or curcumin analog C1, is an activator of transcription factor EB (TFEB) and is used as a research tool compound in molecular and chemical biology.
Combretastatin A4
Cat. No.
AKA-07
CAS No.
117048-59-6
MF
C18H20O5
MW
316.353
Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin.
Nonivamide
Cat. No.
AKA-08
CAS No.
2444-46-4
MF
C17H27NO3
MW
293.407
Nonivamide is a synthetic derivative of natural capsaicin and a TRPV1 agonist.
2-Thioadenosine (Cangrelor intermediate 1)
Cat. No.
AKA-09
CAS No.
43157-50-2
MF
C10H13N5O4S
MW
299.31
2-Thioadenosine (Cangrelor intermediate 1) is a selective A1 adenosine receptor (A1AR) ligand, is a key intermediate of cangrelor
Cangrelor Intermediate
Cat. No.
AKA-10
CAS No.
163706-58-9
MF
C16H22F3N5O4S2
MW
469.498
Cangrelor Intermediate, chemically (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol (C16H22F3N5O4S2, MW 469.50), is a key chiral nucleoside-type intermediate in the synthesis of Cangrelor.
Osimertinib Mesylate Intermediate 1
Cat. No.
AKA-11
CAS No.
1421372-94-2
MF
C20H16FN5O3
MW
393.378
Osimertinib Mesylate Intermediate 1, chemically N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine (C20H16FN5O3, MW 393.37), is a key intermediate in the synthetic route to Osimertinib.
Osimertinib Mesylate
Cat. No.
AKA-12
CAS No.
1421373-66-1
MF
C29H37N7O5S
MW
595.719
Osimertinib mesylate is a third‑generation EGFR inhibitor that suppresses the T790M resistance mutation generated by second‑generation EGFR inhibitors.
Olaparib Intermediate
Cat. No.
AKA-13
CAS No.
763114-26-7
MF
C16H11FN2O3
MW
298.273
Olaparib Intermediate, chemically 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid (C16H11FN2O3, MW 298.27), is a key carboxylic acid intermediate in the synthetic route to Olaparib.
Olaparib
Cat. No.
AKA-14
CAS No.
763113-22-0
MF
C24H23FN4O3
MW
434.471
Olaparib is a small molecule inhibitor of PARP1/PARP2, with weak inhibitory activity against PARP tankyrase‑1.
2-Bromo-5-hydroxybenzaldehyde
Cat. No.
AKA-15
CAS No.
2973-80-0
MF
C7H5BrO2
MW
201.019
2-Bromo-5-hydroxybenzaldehyde is the versatile pharmaceutical intermediate/starting material for the API crisaborole and pexmetinib, and also for specialty and research synthesis.
4-(4-Bromo-3-formylphenoxy)benzonitrile
Cat. No.
AKA-16
CAS No.
906673-54-9
MF
C14H8BrNO2
MW
302.127
4-(4-Bromo-3-formylphenoxy)benzonitrile is a key intermediate for Crisaborole.