APIs & Intermediates
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Vindoline
Cat. No.
AKA-301
CAS No.
2182-14-1
MF
C25H32N2O6
MW
456.53
Vindoline is an indole alkaloid found in Catharanthus roseus, primarily serving as a key biological precursor in the biosynthesis of vinblastine and vincristine.
4'-Demethylepipodophyllotoxin
Cat. No.
AKA-302
CAS No.
6559-91-7
MF
C21H20O8
MW
400.38
4'-Demethylepipodophyllotoxin (4'-DMEP) is a white crystalline lignan natural product derived from podophyllotoxin. It serves as a critical pharmaceutical intermediate for the synthesis of potent antitumor drugs such as etoposide and teniposide, exhibiting notable biological activities including inhibition of microtubule assembly, antitumor, and antiviral effects.
Arecoline hydrobromide
Cat. No.
AKA-303
CAS No.
300-08-3
MF
C8H13NO2.HBr
MW
236.11
Arecoline hydrobromide (CAS 300-08-3), the hydrobromide salt of an alkaloid extracted from the seeds of the betel nut palm (Areca catechu), is a white to off-white crystalline powder. It acts as a cholinergic receptor agonist with parasympathomimetic effects and is clinically used primarily as an anthelmintic (e.g., against tapeworms) and in the treatment of glaucoma. Additionally, it has been investigated for applications such as an antiarrhythmic agent and a pre-exercise supplement.
Esculetin
Cat. No.
AKA-304
CAS No.
305-01-1
MF
C9H6O4
MW
178.14
6,7-Dihydroxycoumarin (also known as esculetin or aesculetin) is an important pharmaceutical intermediate, primarily used for the synthesis of the antiasthmatic drug dimethoxycoumarin. It possesses notable pharmacological activities, including antibacterial, antiasthmatic, expectorant, and antitussive effects, particularly demonstrating inhibitory activity against Shigella species. Clinically, it is commonly used in the treatment of acute bacillary dysentery and chronic bronchitis.
(4S)-4-Hydroxy-L-isoleucine
Cat. No.
AKA-305
CAS No.
55399-93-4
MF
C6H13NO3
MW
147.17
(4S)-4-Hydroxy-L-isoleucine is a non-proteinogenic amino acid extracted from fenugreek (Trigonella foenum-graecum) seeds, recognized as a highly effective hypoglycemic and antidiabetic component.
Berbamine dihydrochloride
Cat. No.
AKA-306
CAS No.
6078-17-7
MF
C37H40N2O6.2(HCl)
MW
681.66
Berbamine hydrochloride is an alkaloid with demonstrated biological activities in elevating white blood cell count, antiarrhythmia, and immunomodulation.









