Scopoletin is an inhibitor of acetylcholinesterase (AChE).

Scopolin is a coumarin isolated from Arabidopsis thaliana (Arabidopsis) roots.

Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells.

Secoisolariciresinol Diglucoside is the minor isomer of Secoisolariciresinol diglucoside in flaxseed.

Sennoside A is an anthraquinone glycoside found in senna (Cassia angustifolia).

Sennoside B is a potent platelet-derived growth factor (PDGF) inhibitor.

Senegenin is a major active component isolated from the root of the Chinese herb Polygala tenuifolia.

Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis.

Shikonin is a major component of a Chinese herbal medicine named zicao and is also a potent TMEM16A chloride channel inhibitor.

Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds.

Sinoacutine is an isoquinoline alkaloid derived from plants of the Menispermaceae family, such as "Sinomenium acutum"or "Sinomenium acutum".

Sipeimine is an inhibitor targeting the PI3K/AKT/NF-κB pathway and NLRP3 inflammasome, which can competitively bind to PI3K and p65.

Songorine is a diterpenoid alkaloid isolated from the genus Aconitum.

Sophoricoside is an isoflavone glycoside isolated from Sophora japonica.

Sparteine is a natural alkaloid acting as a ganglionic blocking agent.

Sweroside is an iridoid glycoside.