Shikonin is a major component of a Chinese herbal medicine named zicao and is also a potent TMEM16A chloride channel inhibitor.

Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds.

Sinoacutine is an isoquinoline alkaloid derived from plants of the Menispermaceae family, such as "Sinomenium acutum"or "Sinomenium acutum".

Sipeimine is an inhibitor targeting the PI3K/AKT/NF-κB pathway and NLRP3 inflammasome, which can competitively bind to PI3K and p65.

Songorine is a diterpenoid alkaloid isolated from the genus Aconitum.

Sophoricoside is an isoflavone glycoside isolated from Sophora japonica.

Sparteine is a natural alkaloid acting as a ganglionic blocking agent.

Sweroside is an iridoid glycoside.

Swertiamarin is a secoiridoid glycoside natural product mainly derived from plants of the genus Swertia (Gentianaceae family).

Tanshinone I is an inhibitor of type IIA human recombinant sPLA2 and rabbit recombinant cPLA2.

Tanshinone IIA is a natural diterpenoid quinone lipid-soluble component derived from the root of the Chinese medicinal herb Salvia miltiorrhiza.

Tectoridin are isoflavone and phytoestrogen isolated from Maackia amurensis that can activate estrogen and thyroid hormone receptors.

Timosaponin A-III is a steroidal saponin natural product derived from the rhizome of the Chinese herb Anemarrhena asphodeloides.

Tubeimoside I is an HSPD1 inhibitor.

Wilforlide A is a bioactive triterpene isolated from Tripterygium wilfordii Hook f.

Wogonin is a naturally occurring mono-flavonoid.