Polymyxin B2
APC-1831
Polymyxin B2
Cat. No.
APC-1831
CAS No.
34503-87-2
MF
C55H96N16O13
MW
1189.45
Polymyxin B2 is a cyclic lipopeptide antibiotic produced by Bacillus polymyxa and is one of the major components of polymyxin B.
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References
Product Name
CAS No.
34503-87-2
MF
C55H96N16O13
MW
1189.45
Specification
98%
Description
Polymyxin B2 is a cyclic lipopeptide antibiotic produced by Bacillus polymyxa and is one of the major components of polymyxin B.
Chemical name:N-[(S)-4-Amino-1-{[(2S,3R)-1-{[(S)-4-amino-1-oxo-1-({(3S,6S,9S,12S,15S,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(R)-1-hydroxyethyl]-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl}amino)butan-2-yl]amino}-3-hydroxy-1-oxobutan-2-yl]amino}-1-oxobutan-2-yl]-6-methylheptanamide
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Availability: In stock
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Specification sheet
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Store under frozen or refrigerated conditions, keep away from strong light and heat.
References
[1].Orwa JA, Govaerts C, Busson R, Roets E, Van Schepdael A, Hoogmartens J. Isolation and structural characterization of polymyxin B components. J Chromatogr A. 2001;912(2):369-373. doi: 10.1016/S0021-9673(01)00585-4
[2].Wilkinson S, Lowe LA. Structures of polymyxin B2 and polymyxin E1. Nature. 1964;204:185. doi: 10.1038/204185a0
[3].Roberts KD, Azad MAK, Wang J, Horne AS, Thompson PE, Nation RL, et al. Antimicrobial activity and toxicity of the major lipopeptide components of polymyxin B and colistin: last-line antibiotics against multidrug-resistant Gram-negative bacteria. ACS Infect Dis. 2015;1(11):568-575. doi: 10.1021/acsinfecdis.5b00085
Disclaimer
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