OSW-1
APC-1805
OSW-1
Cat. No.
APC-1805
CAS No.
145075-81-6
MF
C47H68O15
MW
873.04
OSW-1 is the highly cytotoxic cholestane/steroidal saponin originally isolated from the bulbs of Ornithogalum saundersiae. Its structure is commonly described as 3β,16β,17α-trihydroxycholest-5-en-22-one bearing an acylated disaccharide at C-16.
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Technical Data
Description
Storage and Shipping
References
Product Name
CAS No.
145075-81-6
MF
C47H68O15
MW
873.04
Specification
98%
Description
OSW-1 is the highly cytotoxic cholestane/steroidal saponin originally isolated from the bulbs of Ornithogalum saundersiae. Its structure is commonly described as 3β,16β,17α-trihydroxycholest-5-en-22-one bearing an acylated disaccharide at C-16. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g Availability: In stock
Documents
Certificate of Analysis (COA), Specification Sheet, HPLC, 1HNMR, 13CNMR, IR, MS, Safety Data Sheet (SDS/MSDS) etc.
Storage and Shipping
Store in a cool and dry place, avoid strong light and high temperature
References
[1].Kubo S, Mimaki Y, Terao M, Sashida Y, Nikaido T, Ohmoto T. Acylated cholestane glycosides from the bulbs of Ornithogalum saundersiae. Phytochemistry. 1992;31(11):3969-3973. doi:10.1016/S0031-9422(00)97565-4.
[2].Mimaki Y, Kuroda M, Kameyama A, Sashida Y, Hirano T, Oka K, et al. Cholestane glycosides with potent cytostatic activities on various tumor cells from Ornithogalum saundersiae bulbs. Bioorg Med Chem Lett. 1997;7:633-636. doi:10.1016/S0960-894X(97)00071-1.
[3].Elgehama A. Selective obstruction of the mTORC2 complex by a naturally occurring cholestane saponin (OSW-1) for inhibiting prostate cancer cell growth. J Asian Nat Prod Res. 2021;23(12):1111-1120. doi:10.1080/10286020.2021.1951255.
[2].Mimaki Y, Kuroda M, Kameyama A, Sashida Y, Hirano T, Oka K, et al. Cholestane glycosides with potent cytostatic activities on various tumor cells from Ornithogalum saundersiae bulbs. Bioorg Med Chem Lett. 1997;7:633-636. doi:10.1016/S0960-894X(97)00071-1.
[3].Elgehama A. Selective obstruction of the mTORC2 complex by a naturally occurring cholestane saponin (OSW-1) for inhibiting prostate cancer cell growth. J Asian Nat Prod Res. 2021;23(12):1111-1120. doi:10.1080/10286020.2021.1951255.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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