Trigonelline
APC-1089
Trigonelline
Cat. No.
APC-1089
CAS No.
535-83-1
MF
C7H7NO2
MW
137.14
Trigonelline is an alkaloid with potential activity that can be isolated from fenugreek or motherwort, and Trigonelline is a potent Nrf2 inhibitor.
Technical Service Need help? Our team of experienced experts is here for you with full support.
86-28-85159085 
info@aktin.com Technical Data
Description
Storage and Shipping
References
Product Name
CAS No.
535-83-1
MF
C7H7NO2
MW
137.14
Specification
98%
Research Area
Anti-diabetic, neuroprotective, and anti-migraine
Description
Trigonelline is an alkaloid with potential activity that can be isolated from fenugreek or motherwort, and Trigonelline is a potent Nrf2 inhibitor. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g Availability: In stock
Storage and Shipping
Store under frozen or refrigerated conditions, keep away from strong light and heat.
References
[1]. Ilavenil S, et al. Trigonelline protects the cardiocyte from hydrogen peroxide induced apoptosis in H9c2 cells. Asian Pac J Trop Med. 2015 Apr;8(4):263-8.
[2]. Joanna Folwarczna, et al. Effects of Trigonelline, an Alkaloid Present in Coffee, on Diabetes-Induced Disorders in the Rat Skeletal System. Nutrients. 2016 Mar; 8(3): 133.
[3]. A Arlt, et al. Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity. Oncogene. 2013 Oct;32(40):4825-35.
[4]. Ozçelik B, et al. Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids. Pharm Biol. 2011 Apr;49(4):396-402.
[5]. Su Y, et al. Ferroptosis, a novel pharmacological mechanism of anti-cancer drugs. Cancer Lett. 2020 Jul 28;483:127-136.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
Related Products
APC-1809
(-)-Curine
CAS No.:436-05-5
MF:C36H38N2O6
APC-1808
Fusicoccin from Fusicoccum amygdali
CAS No.:20108-30-9
MF:C36H56O12
APC-1806
Albine formate
CAS No.:53915-26-7(free base)
MF:C15H22N2O3
APC-1805
OSW-1
CAS No.:145075-81-6
MF:C47H68O15
APC-1804
Angustifoline formate
CAS No.:550-43-6（free base）
MF:C15H24N2O3
APC-1803
Aloe-emodin 8-O-β-D-(6'-galloyl)glucopyranoside
CAS No.:1374014-36-4
MF:C28H24O14
APC-1800
(+)-allo-Hydroxycitric acid calcium salt /Hibiscus acid calcium
CAS No.:27750-11-4 (free base)
MF: C12H10Ca3O16
APC-1799
Isoengeletin
CAS No.:30987-58-7
MF:C21H22O10
APC-1798
Isoastilbin
CAS No.:54081-48-0
MF:C21H22O11
APC-1797
(-)-3-Dehydroshikimic acid
CAS No.:2922-42-1
MF:C7H8O5
* Some statements have not been evaluated by national authorities. * Some products are not intended to diagnose, treat, cure, or prevent any disease. * For literature supporting, please contact us directly.
