Coptisine Chloride
APC-1084
Coptisine Chloride
Cat. No.
APC-1084
CAS No.
6020-18-4
MF
C19H14ClNO4
MW
355.8
Coptisine Chloride is an alkaloid from Chinese goldthread, and acts as an efficient uncompetitive IDO inhibitor, Coptisine chloride is a potent H1N1 neuraminidase (NA-1) inhibitorand can be used for influenza A (H1N1) infection.
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Technical Data
Description
Storage and Shipping
References
Product Name
CAS No.
6020-18-4
MF
C19H14ClNO4
MW
355.8
Specification
98%
Research Area
Antibacterial, anti-inflammatory, and potent hypoglycemic
Description
Coptisine Chloride is an alkaloid from Chinese goldthread, and acts as an efficient uncompetitive IDO inhibitor, Coptisine chloride is a potent H1N1 neuraminidase (NA-1) inhibitorand can be used for influenza A (H1N1) infection. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g Availability: In stock
Documents
Certificate of Analysis (COA), Specification Sheet, HPLC, 1HNMR, 13CNMR, IR, MS, Safety Data Sheet (SDS/MSDS) etc.
Storage and Shipping
Store under frozen or refrigerated conditions, keep away from strong light and heat.
References
[1]. Yu D, et al. The IDO inhibitor coptisine ameliorates cognitive impairment in a mouse model of Alzheimer's disease. J Alzheimers Dis. 2015;43(1):291-302.
[2]. He K, et al. The safety and anti-hypercholesterolemic effect of coptisine in Syrian golden hamsters. Lipids. 2015 Feb;50(2):185-94.
[3]. Rao PC, et al. Coptisine-induced cell cycle arrest at G2/M phase and reactive oxygen species-dependent mitochondria-mediated apoptosis in non-small-cell lung cancer A549 cells. Tumour Biol. 2017 Mar;39(3):1010428317694565.
[4]. Zhou X, et al. Inhibition activity of a traditional Chinese herbal formula Huang-Lian-Jie-Du-Tang and its major components found in its plasma profile on neuraminidase-1. Sci Rep. 2017 Nov 14;7(1):15549.
[2]. He K, et al. The safety and anti-hypercholesterolemic effect of coptisine in Syrian golden hamsters. Lipids. 2015 Feb;50(2):185-94.
[3]. Rao PC, et al. Coptisine-induced cell cycle arrest at G2/M phase and reactive oxygen species-dependent mitochondria-mediated apoptosis in non-small-cell lung cancer A549 cells. Tumour Biol. 2017 Mar;39(3):1010428317694565.
[4]. Zhou X, et al. Inhibition activity of a traditional Chinese herbal formula Huang-Lian-Jie-Du-Tang and its major components found in its plasma profile on neuraminidase-1. Sci Rep. 2017 Nov 14;7(1):15549.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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