Bullatine A
APC-1005
Bullatine A
Cat. No.
APC-1005
CAS No.
1354-84-3
MF
C22H33NO2
MW
343.5
Bullatine A is a diterpenoid alkaloid and a potent P2X7 antagonist.
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Description
Storage and Shipping
References
Product Name
CAS No.
1354-84-3
MF
C22H33NO2
MW
343.5
Specification
98%
Research Area
Anti-rheumatic, anti-inflammatory and anti-nociceptive
Description
Bullatine A is a diterpenoid alkaloid and a potent P2X7 antagonist. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g Availability: In stock
Storage and Shipping
Store under frozen or refrigerated conditions, keep away from strong light and heat.
References
[1]. Li J, et al. Bullatine A, a diterpenoid alkaloid of the genus Aconitum, could attenuate ATP-induced BV-2 microglia death/apoptosis via P2X receptor pathways. Brain Res Bull. 2013 Aug;97:81-5.
[2]. Huang Q, et al. Bullatine A stimulates spinal microglial dynorphin A expression to produce anti-hypersensitivity in a variety of rat pain models. J Neuroinflammation. 2016 Aug 30;13(1):214.
[3]. Liu S, et al. Bullatine A exerts anti-inflammatory effects by inhibiting the ROS/JNK/NF-κB pathway and attenuating systemic inflammatory responses in mice. Pharm Biol. 2022 Dec;60(1):1840-1849.
[4]. Wang Z, et al. Bullatine A suppresses glioma cell growth by targeting SIRT6. Heliyon. 2024 Dec 24;11(1):e41440.
[5]. Zhang JR, et al. Bullatine A has an antidepressant effect in chronic social defeat stress mice; Implication of microglial inflammasome. Brain Res Bull. 2023 Apr;195:130-140.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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