6-Acetyllarixol
APC-976
6-Acetyllarixol
Cat. No.
APC-976
CAS No.
4608-49-5
MF
C22H36O3
MW
348.5
6-Acetyllarixol is a potent and selective TRPC6 inhibitor.
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Description
Storage and Shipping
References
Product Name
CAS No.
4608-49-5
MF
C22H36O3
MW
348.5
Specification
98%
Research Area
Anti-HPV, neuroprotective, endothelial protection
Description
6-Acetyllarixol is a potent and selective TRPC6 inhibitor. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g Availability: In stock
Storage and Shipping
Store under frozen or refrigerated conditions, keep away from strong light and heat.
References
[1]. Urban N, et al. Identification and Validation of Larixyl Acetate as a Potent TRPC6 Inhibitor. Mol Pharmacol. 2016 Jan;89(1):197-213.
[2]. Liao HR, et al. Larixol inhibits fMLP-induced superoxide anion production and chemotaxis by targeting the βγ subunit of Gi-protein of fMLP receptor in human neutrophils. Biochem Pharmacol. 2022 Jul;201:115091.
[3]. Chen X, et al. The TRPC6 inhibitor, larixyl acetate, is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction. J Neuroinflammation. 2019 Jan 31;16(1):21.
[4]. Wang J, et al. The analgesic action of larixyl acetate, a potent TRPC6 inhibitor, in rat neuropathic pain model induced by spared nerve injury. J Neuroinflammation. 2020 Apr 16;17(1):118.
[5]. Jia M, et al. Larixyl acetate, a TRPC6 inhibitor, attenuates pressure overload‑induced heart failure in mice. Mol Med Rep. 2024 Mar;29(3):49.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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