Physcion
APC-215
Physcion
Cat. No.
APC-215
CAS No.
521-61-9
MF
C16H12O5
MW
284.2635
Physcion an anthraquinone derivative derived from the traditional Chinese medicine rhubarb, is an effective 6-phosphogluconate dehydrogenase inhibitor with blood-brain barrier permeability.
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Description
Storage and Shipping
References
Product Name
CAS No.
521-61-9
MF
C16H12O5
MW
284.2635
Specification
98%
Research Area
Anti-inflammatory, antibacterial, and anticancer
Description
Physcion an anthraquinone derivative derived from the traditional Chinese medicine rhubarb, is an effective 6-phosphogluconate dehydrogenase inhibitor with blood-brain barrier permeability. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g Availability: In stock
Storage and Shipping
Store under frozen or refrigerated conditions, keep away from strong light and heat
References
[1]. Lin R, et al. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat Cell Biol. 2015 Nov;17(11):1484-96.
[2]. Pang MJ, et al. Physcion, a naturally occurring anthraquinone derivative, induces apoptosis and autophagy in human nasopharyngeal carcinoma. Acta Pharmacol Sin. 2016 Dec;37(12):1623-1640.
[3]. Dong X, et al. Physcion Protects Rats Against Cerebral Ischemia-Reperfusion Injury via Inhibition of TLR4/NF-kB Signaling Pathway. Drug Des Devel Ther. 2021 Jan 25;15:277-287.
[4]. Liu X, et al. Physcion, a novel anthraquinone derivative against Chlamydia psittaci infection. Vet Microbiol. 2023 Apr;279:109664. doi: 10.1016/j.vetmic.2023.109664.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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