2'-O-Galloylhyperin
APC-002
2'-O-Galloylhyperin
Cat. No.
APC-002
CAS No.
53209-27-1
MF
C28H24O16
MW
616.48
2''-O-Galloylhyperin upregulates SIRT1/Nrf2 signaling, inhibits NF-κB and MAPK (ERK1/2, p38, JNK) phosphorylation, suppresses TSHR activation, reduces ROS accumulation, and enhances SOD and GSH-Px activities.
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Technical Data
Description
Storage and Shipping
References
Product Name
CAS No.
53209-27-1
MF
C28H24O16
MW
616.48
Specification
98%
Research Area
Anti-oxidative and anti-inflammatory
Description
2''-O-Galloylhyperin upregulates SIRT1/Nrf2 signaling, inhibits NF-κB and MAPK (ERK1/2, p38, JNK) phosphorylation, suppresses TSHR activation, reduces ROS accumulation, and enhances SOD and GSH-Px activities. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g Availability: In stock
Storage and Shipping
Store under frozen or refrigerated conditions, keep away from strong light and heat.
References
[1]. Wang P, et al. 2'-O-Galloylhyperin Isolated From Pyrola incarnata Fisch. Attenuates LPS-Induced Inflammatory Response by Activation of SIRT1/Nrf2 and Inhibition of the NF-κB Pathways in Vitro and Vivo. Front Pharmacol. 2018 Jun 27;9:679.
[2]. Zhang SD, et al. 2'O-galloylhyperin attenuates LPS-induced acute lung injury via up-regulation antioxidation and inhibition of inflammatory responses in vivo. Chem Biol Interact. 2019;304:20-27.
[3]. Guo Y, et al. 2'-O-Galloylhyperin Prevents Tissue Remodeling in Thyroid Eye Disease: Prospects as a Thyrotropin Receptor Antagonist. J Clin Endocrinol Metab. 2025;110(8):e2711-e2722.
Disclaimer
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