AkVEri^® is dedicated to providing high-purity, traceable life science reagents and customized solutions to global pharmaceutical enterprises, research institutions, contract research organizations (CROs), and quality control laboratories. Our offerings support key application areas such as drug discovery, analytical method development and validation, quality control, process research, pharmacokinetics and metabolism research, novel formulation development, and pharmaceutical registration support.

High-Purity Life Science Reagents for Research and Development Needs

AkVEri^® provides high-purity research reagents across six functional categories centered on drug development and quality control scenarios:

AkVEri^® Natural Product Reference Standards

We provide botanical phytochemical monomers and natural product reference standards from a wide range of sources and with diverse structures, covering alkaloids, flavonoids, terpenoids, phenolic acids and polyphenols, saponins, lignans, coumarins, quinones, steroids, glycosides, plant metabolites and degradation products, polysaccharide markers, etc.
Applications: Natural product drug discovery, botanical drug development and medicinal plant research, fingerprint analysis, marker component screening and plant-derived product quality control, compound library construction and high-throughput screening, target identification and mechanism of action research, lead compound discovery and structure-activity relationship (SAR) analysis, etc.

AkVEri^® Pharmaceutical Impurities and Degradation Products

Our portfolio supplies high-purity impurity reference standards for drug quality research and analytical method development, covering various types of impurities across the entire drug lifecycle, including:
• Process-related impurities such as starting materials, synthetic intermediates, side-reaction products, and residual solvents；
• D egradation products such as oxidation, reduction, hydrolysis products, and light/thermal degradation products;
• Key impurities formed by the degradation of the API itself; 
• Isomeric impurities such as stereoisomers, diastereomers, and geometric isomers; 
• Drug metabolites generated through in vivo metabolic transformation ；
• Alerting structure compounds, nitrosamines, halogenated alkanes, and other potential genotoxic impurities .
In addition, we provide flexible customized services, including the targeted synthesis of specific impurities, isolation and purification of complex impurities, impurity profiling, and structural identification.
Applications: Qualitative identification and assay determination of APIs and preparations, impurity profiling, batch consistency evaluation, analytical method development and validation, reference standard suitability assessment, forced degradation testing, stability investigation, and drug registration-related research, genotoxic impurity assessment, and mutagenic impurity control strategy research, etc .

AkVEri^® ADC Payloads and Related Reagents

The line offers ADC payloads, payload derivatives, and related research materials covering multiple mechanisms of action, including: 
• Microtubule inhibitory payloads ；
• DNA-damaging payloads ；
• Topoisomerase inhibitory payloads ；
• RNA polymerase inhibitory payloads ；
• Immunomodulatory payloads ；
• Payload active derivatives ；
• Linker-ready payload intermediates (including linkage-site modifications) ；
• ADC payload-related impurities, payload metabolites, and degradation products.
For specific research needs, customized synthesis services for cytotoxic small molecules are also available.
Applications: Early-stage ADC discovery, candidate payload screening, linker design and synthesis, conjugation process development, in vitro activity evaluation, pharmacokinetic (PK) and pharmacodynamic (PD) research, ADC-related impurity analysis and stability assessment, free payload detection, and ADC degradation product research, etc.
Note: Certain ADC payloads possess high cytotoxicity and must be used in laboratories equipped with corresponding protective conditions.

AkVEri^® Peptides and Peptide Research Reagents

We supply high-purity peptide products and customization services for drug development and bioanalysis, encompassing:
• Pharmacologically active peptides (including peptide hormones and analogs, receptor agonists/antagonists peptides, enzyme substrate peptides, signaling pathway research peptides) ;
• Peptides for immunization and diagnostics (antigenic peptides and B-cell epitope peptides) ;
• Structurally modified and labeled peptides (fluorescent labeling, biotin labeling, stable isotope labeling, and various chemically modified peptides) ;
• Special structure peptides (cyclic peptides, branched peptides) ;
• Peptide quality control materials (peptide impurities, degradation products) .
Meanwhile, flexible custom sequence peptide synthesis services are available, which can provide different lengths, purities, terminal modifications, unnatural amino acids, and packaging specifications according to project needs, meeting specific requirements at various stages from foundational research to drug quality research.
Applications: Peptide activity evaluation, receptor binding research and signaling pathway research, peptide immunology research (antigen epitope screening, B-cell epitope peptide design), peptide drug quality research (purity analysis, impurity and degradation product control), bioanalytical method development (LC-MS/MS quantification, ELISA, etc.), etc.

AkVEri^® Vaccine Adjuvants and Immunological Research Materials

The catalog covers high-purity adjuvants and related materials for vaccine research, immune mechanism exploration, and formulation development, including:
• Classical adjuvants (aluminum salt adjuvants) ;
• Immunostimulants (including Toll-like receptor agonists, lipid immunostimulants, nucleic acid immunostimulants, saponin adjuvants such as QS-21 ( CAS 141256-04-4), as well as cytokines and immunomodulatory materials) ;
• Emulsion-type adjuvant-related materials ;
• Materials for mucosal immunity research ;
• Adjuvant reference standards and related impurities ;
• Excipients for vaccine formulation research
On this basis, adjuvant screening, formulation optimization, and customized immunomodulatory scheme design services are also provided.
Applications: Antigen screening, immunogenicity evaluation, adjuvant combination research, cellular immunity and humoral immunity research, vaccine delivery system development, humoral immune and cellular immune response analysis, vaccine stability research, mucosal immunity research, and novel immunomodulator evaluation, etc.
Note: Unless specified otherwise, related products are restricted solely to in vitro research, analytical research, or non-clinical scientific research uses, and must not be directly used for human immunization.

AkVEri^® RNA Delivery Systems and Related Materials

We provide high-purity RNA delivery systems and related materials for the research and development of mRNA, siRNA, saRNA, miRNA, and other nucleic acid drugs, including:
• Ionizable Lipids:Used for efficient encapsulation of nucleic acid drugs and to achieve endosomal escape;
• Cationic Lipids: Used for nucleic acid complexation and transfection research;
• Phospholipids: Constituting the lipid bilayer framework of LNPs; 
• Cholesterol and its Derivatives: Regulating membrane fluidity and stability; 
• PEGylated Lipids: Regulating particle size and extending circulation time in vivo;
• Helper Lipids: Optimizing LNP formulation stability and delivery efficiency;
• Targeted Lipids and Ligand Modification Materials: Achieving active targeted delivery to specific tissues or cells;
• LNP Formulations and Research Materials: Lipid nanoparticle research materials, delivery system screening materials;
• Quality Control Materials: Lipid-related impurities and degradation products.
In addition, custom lipid and lipid derivative synthesis as well as formulation optimization services are available, which can customize different structures, chain lengths, linking groups, biodegradable bonds, and targeting ligands according to research projects, meeting diversified needs from proof-of-concept to delivery system optimization.
Applications: LNP formulation screening, nanoparticle preparation, nucleic acid encapsulation and encapsulation rate research, cellular uptake and endosomal escape evaluation, tissue targeting research, and delivery efficiency optimization for nucleic acid drugs such as mRNA, siRNA, saRNA, miRNA, etc.

Note: Products are supplied for scientific research use only. Unless explicitly stated otherwise in product documentation, they must not be used for human or animal diagnosis, treatment, prevention, food, or clinical uses.

Quality Assurance and Technical Support, Escorting the Entire R&D Process

The quality of research reagents directly affects the accuracy of analytical results, the reproducibility of experiments, and the reliability of research conclusions. AkVEri® products possess clear quality specifications and provide corresponding analytical and technical documentation based on product types: 
• Chemical name, molecular formula, molecular weight, and structural information
• CAS number or other compound identification information 
• Quality standards and analytical methods 
• Characterization data such as HPLC, UPLC, LC-MS, GC-MS, NMR, etc. 
• Residual solvents, moisture, elemental impurities, or related impurity data 
• Storage, stability, and operational recommendations

Our technical team brings together multidisciplinary professional expertise in organic chemistry, natural products, analytical chemistry, peptide chemistry, and drug quality research to provide deep technical support at all stages of the project:
• Consultation on the selection and matching of products and target compounds 
• Rationality assessment of analytical standards and specifications 
• Synthetic route design and project technical feasibility demonstration
• I mpurity source tracing and analysis of its formation mechanism
• Professional review and re-check of analytical testing data
• Guidance on storage conditions, stability, and standardized operations
• Communication and collaborative formulation of customized project technical plans
• Preparation of technical documentation and certification materials required for scientific research uses
• Product application training oriented toward R&D and quality teams
• Overall coordination of relevant technical data in registration application research

Customized Services: Solutions Beyond the Catalog

For rare, commercially unavailable, or special specification products, AkVEri® provides flexible customized R&D and supply services:
• Isolation and purification of natural products;
• Custom synthesis of small molecule compounds;
• Preparation of pharmaceutical impurities and degradation products;
• Synthesis of drug metabolites;
• Synthesis of ADC payloads and payload derivatives;
• Custom peptide synthesis and modification;
• Customization of vaccine adjuvants and RNA delivery lipid materials; 
• Preparation of stable isotope-labeled compounds;
• Global sourcing for rare compounds and feasibility assessment for high-difficulty projects.

We support milligram-scale to gram-scale supply, and can customize purity, concentration, and packaging specifications according to requirements. Each project formulates an exclusive manufacturing, purification, and quality control scheme based on the target structure, quality requirements, quantity, application, and delivery timeline.

Why Choose AkVEri^® ?

✔ Continuously Expanding Compound Library : Covering more than 2,000 high-performance core scaffolds, and continuously expanding at a speed of dozens of types per month, providing support for high-throughput screening and new drug discovery. 
✔ Full-Process Quality Traceability System: Each batch of products undergoes analytical characterization, clearly recording batch, source, production, and analytical information, ensuring high purity and data integrity, and providing support for drug R&D and quality research.
✔ Deep Cross-Disciplinary Integration Capability : Fusing expertise across multiple fields such as organic chemistry, natural products, analytical chemistry, peptide chemistry, and drug quality research to provide multidimensional solution ideas for complex technical difficulties .
✔ Spanning the Entire Drug R&D Lifecycle: The product portfolio covers cutting-edge fields such as natural products, drug impurities, ADCs, peptides, vaccine adjuvants, and RNA delivery, responding to R&D needs throughout the process from front-end discovery to quality control.
✔ Flexible Customization and Elastic Supply : Providing customization services for rare compounds, impurities, metabolites, high-activity payloads, peptides, and novel lipids, and can flexibly supply milligram-scale to kilogram-scale and above products according to the R&D stage, achieving transition from the laboratory to industrialization.

Partner with Us

Whether there is a need for conventional catalog products, or rare natural compounds, pharmaceutical impurities, ADC payloads, custom peptides, vaccine adjuvants, and RNA delivery system-related materials, we can provide a solution covering reagent supply, technical documentation, and expert support.
We are dedicated to supporting the steady progression of research with solid professional capabilities and high-quality products. Partnering with AkVEri® helps accelerate drug innovation and scientific breakthroughs.

Welcome to meet us: CPHI Milan 2026 from Oct. 6-8, Booth No.: 4H109