可美替尼半富马酸盐是一种有效的选择性 MEK1/2 抑制剂，可抑制 MEK 激酶活性并调控 RAF–MEK–ERK 信号通路，在靶向抗肿瘤药物研发中具有重要应用价值。
化学名称：(E)-but-2-enedioic acid;bis([3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone)
包装：1kg/袋，5kg/袋，10kg/袋
供货情况：现货供应
API Current Development Status: A3---Process Development / Scale-Up
Reference: 
Aktin major API development processes:
A1.Feasibility / Route Development
A2.Laboratory Process Development
A3.Process Development / Scale-Up
A4.GMP Clinical Development
A5.Commercial GMP Supply

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[2].Larkin J, Ascierto PA, Dréno B, Atkinson V, Liszkay G, Maio M, et al. Combined vemurafenib and cobimetinib in BRAF-mutated melanoma. N Engl J Med. 2014;371(20):1867-76. doi: 10.1056/NEJMoa1408868

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