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AKA-213
Ipidacrine Hydrochloride Hydrate
Cat. No.
AKA-213
CAS No.
118499-70-0
MF
C12H19ClN2O
MW
242.75
Ipidacrine hydrochloride is an active and brain-penetrant acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitor. It also acts as a partial agonist of M2-cholinergic receptors and exhibits reversible cholinesterase inhibition.
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Documents
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References
Product Name
Ipidacrine Hydrochloride Hydrate
CAS No.
118499-70-0
MF
C12H19ClN2O
MW
242.75
Specification
医药级
Research Area
Cognitive impairment
Description
Ipidacrine hydrochloride is an active and brain-penetrant acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitor. It also acts as a partial agonist of M2-cholinergic receptors and exhibits reversible cholinesterase inhibition. Packing: 1kg/bag; 25kg/drum or as request Availability: In stock
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Kojima J, Onodera K, Ozeki M, et al. Ipidacrine (NIK-247): A review of multiple mechanisms as an antidementia agent. CNS Drug Reviews. 1998;4(3):247-259.
[2]. Burov Y, Cadysheva L, Rodakidze T, et al. Pharmacological effects of amiridin. European Journal of Pharmacology. 1990;183:1464.
[3]. Bykov V, Gushchina E, Morozov S, et al. Ipidacrine (Axamon), a reversible cholinesterase inhibitor, improves erectile function in male rats with diabetes mellitus-induced erectile dysfunction. Sexual Medicine. 2022;10(1):100477.
[4]. NCATS Inxight Drugs. Ipidacrine hydrochloride monohydrate[EB/OL].
[5]. Onodera K, Kojima J, Wachi M. Ipidacrine (NIK-247), a novel antidementia, rapidly enters the brain and improves scopolamine-induced amnesia in rats during the Morris water maze task. Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 1998;18(2):33-37.
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* Some statements have not been evaluated by national authorities. * Some products are not intended to diagnose, treat, cure, or prevent any disease. * For literature supporting, please contact us directly.
