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AKA-347
Vigabatrin
Cat. No.
AKA-347
CAS No.
68506-86-5
MF
C6H11NO2
MW
129.16
Vigabatrin is a vinyl derivative of the inhibitory neurotransmitter GABA. It is an active and irreversible inhibitor of GABA transaminase.
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Product Name
Vigabatrin
CAS No.
68506-86-5
MF
C6H11NO2
MW
129.16
Specification
98%
Research Area
Selectively and irreversibly inhibits GABA-transaminase (GABA-T)
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
Description
Vigabatrin is a vinyl derivative of the inhibitory neurotransmitter GABA. It is an active and irreversible inhibitor of GABA transaminase. Packing: 1kg/bag; 25kg/drum or as request Availability: DMF preparation & filing in progress
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Broeer, et al. Vigabatrin for focal drug delivery in epilepsy: Bilateral microinfusion into the subthalamic nucleus is more effective than intranigral or systemic administration in a rat seizure model. Neurobiology of Disease (2012), 46(2), 362-376.
[2]. Jakob Plum, et al. The anti-epileptic drug substance vigabatrin inhibits taurine transport in intestinal and renal cell culture models. Int J Pharm. 2014 Oct 1;473(1-2):395-7.
[3]. Gaily, Eija Vigabatrin monotherapy for infantile spasms. Expert Review of Neurotherapeutics (2012), 12(3), 275-286.
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