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AKA-185
Tauroursodeoxycholic Acid
Cat. No.
AKA-185
CAS No.
14605-22-2
MF
C26H45NO6S
MW
499.71
Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an active endoplasmic reticulum (ER) stress inhibitor that also inhibits ERK and reduces caspase-3/caspase-12 expression.
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Product Name
Tauroursodeoxycholic Acid
CAS No.
14605-22-2
MF
C26H45NO6S
MW
499.71
Specification
98%
Research Area
Primary biliary cholangitis and specific cholestatic liver diseases
Description
Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an active endoplasmic reticulum (ER) stress inhibitor that also inhibits ERK and reduces caspase-3/caspase-12 expression. Packing: 1kg/bag; 25kg/drum or as request Availability: In stock
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Kim SY, et al. Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK via PKCα-mediated MKP-1 induction. Cardiovascular Research. 2011 Nov 1;92(2):307-16.
[2]. Qin Y, et al. Tauroursodeoxycholic Acid Attenuates Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-deficient Mice by Inhibiting Endoplasmic Reticulum Stress. European Journal of Vascular and Endovascular Surgery. 2017 Mar;53(3):337-345.
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