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AKA-128
Chenodeoxycholic Acid
Cat. No.
AKA-128
CAS No.
474-25-9
MF
C24H40O4
MW
392.572
Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
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References
Product Name
Chenodeoxycholic Acid
CAS No.
474-25-9
MF
C24H40O4
MW
392.572
Specification
USP/EP
Research Area
Dissolving cholesterol gallstones
Description
Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism. Packing: 1kg/bag; 25kg/drum or as request Availability: 1 metric ton per month
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Stauffer AT, et al. Chenodeoxycholic acid and deoxycholic acid inhibit 11 beta-hydroxysteroid dehydrogenase type 2 and cause cortisol-induced transcriptional activation of the mineralocorticoid receptor. The Journal of Biological Chemistry. 2002 Jul 19;277(29):26286-92
[2]. Casaburi I, et al. Chenodeoxycholic acid through a TGR5-dependent CREB signaling activation enhances cyclin D1 expression and promotes human endometrial cancer cell proliferation. Cell Cycle. 2012 Jul 15;11(14):2699-710
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