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AKA-12
Osimertinib Mesylate
Cat. No.
AKA-12
CAS No.
1421373-66-1
MF
C29H37N7O5S
MW
595.719
Osimertinib mesylate is a third‑generation EGFR inhibitor that suppresses the T790M resistance mutation generated by second‑generation EGFR inhibitors.
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Description
Documents
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References
Product Name
Osimertinib Mesylate
CAS No.
1421373-66-1
MF
C29H37N7O5S
MW
595.719
Specification
99%
Research Area
Oncology
Description
Osimertinib mesylate is a third‑generation EGFR inhibitor that suppresses the T790M resistance mutation generated by second‑generation EGFR inhibitors. Packing: 1kg/bag; 25kg/drum or as request Availability: In stock
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Cross DA, et al. AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cancer Discovery. 2014 Sep;4(9):1046-61.
[2]. [2]Hirano T, et al. Pharmacological and Structural Characterizations of Naquotinib, a Novel Third-Generation EGFR Tyrosine Kinase Inhibitor, in EGFR-Mutated Non-Small Cell Lung Cancer. Molecular Cancer Therapeutics. 2018 Apr;17(4):740-750.
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