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AKA-02
Tizanidine Hydrochloride
Cat. No.
AKA-02
CAS No.
64461-82-1
MF
C9H9Cl2N5S
MW
290.17
Tizanidine Hydrochloride is an α2‑adrenergic receptor agonist that inhibits the release of neurotransmitters from CNS norepinephrine‑activated neurons.
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Description
Documents
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References
Product Name
Tizanidine Hydrochloride
CAS No.
64461-82-1
MF
C9H9Cl2N5S
MW
290.17
Specification
USP/EP/CP
Research Area
Muscle Relaxant
Description
Tizanidine Hydrochloride is an α2‑adrenergic receptor agonist that inhibits the release of neurotransmitters from CNS norepinephrine‑activated neurons. Packing: 1kg/bag; 25kg/drum or as request Availability: In stock
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Kamen L, et al. A practical overview of tizanidine use for spasticity secondary to multiple sclerosis, stroke, and spinal cord injury. Current Medical Research and Opinion. 2008 Feb;24(2):425-39.
[2]. Granfors MT, Backman JT, Laitila J, Neuvonen PJ. Tizanidine is mainly metabolized by cytochrome p450 1A2 in vitro. British Journal of Clinical Pharmacology. 2004 Mar;57(3):349-53. doi: 10.1046/j.1365-2125.2003.02028.x. PMID: 14998432; PMCID: PMC1884447.
[3]. Zhao L, Zhao G, Xue Q. Tizanidine (Hydrochloride) Inhibits A549 Lung Cancer Cell Proliferation and Motility Through Regulating Nischarin. OncoTargets and Therapy. 2020 Jan 10;13:291-298.
[4]. Rodríguez-Palma EJ, et al. Sex-dependent antiallodynic effect of α2 adrenergic receptor agonist tizanidine in rats with experimental neuropathic pain. European Journal of Pharmacology. 2022 Apr 5;920:174855.
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