OSW-1
产品编号
APC-1805
CAS号码
145075-81-6
分子式
C47H68O15
分子量
873.04
145075-81-6
C47H68O15
873.04
98%
OSW-1 is the highly cytotoxic cholestane/steroidal saponin originally isolated from the bulbs of Ornithogalum saundersiae. Its structure is commonly described as 3β,16β,17α-trihydroxycholest-5-en-22-one bearing an acylated disaccharide at C-16 Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g Availability: In stock
[1].Kubo S, Mimaki Y, Terao M, Sashida Y, Nikaido T, Ohmoto T. Acylated cholestane glycosides from the bulbs of Ornithogalum saundersiae. Phytochemistry. 1992;31(11):3969-3973. doi:10.1016/S0031-9422(00)97565-4.
[2].Mimaki Y, Kuroda M, Kameyama A, Sashida Y, Hirano T, Oka K, et al. Cholestane glycosides with potent cytostatic activities on various tumor cells from Ornithogalum saundersiae bulbs. Bioorg Med Chem Lett. 1997;7:633-636. doi:10.1016/S0960-894X(97)00071-1.
[3].Elgehama A. Selective obstruction of the mTORC2 complex by a naturally occurring cholestane saponin (OSW-1) for inhibiting prostate cancer cell growth. J Asian Nat Prod Res. 2021;23(12):1111-1120. doi:10.1080/10286020.2021.1951255.
*本产品不用于诊断、治疗、治愈或预防任何疾病,仅供科研研究使用。