咖啡醇
APC-978
咖啡醇
产品编号
APC-978
CAS号码
469-83-0
分子式
C20H28O3
分子量
316.4
基本信息
产品描述
仓储与运输
参考文献
中文名称
英文名称
Cafestol
CAS号码
469-83-0
分子式
C20H28O3
分子量
316.4
规格
98%
Research Area
Anti-inflammatory, anti-angiogenic and anti-diabetic
产品描述
咖啡醇是二萜类化合物和 ERK2 的抑制剂。 包装: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g 供货情况: 现货供应
文件支持
Certificate of Analysis (COA), Specification Sheet, HPLC, 1HNMR, 13CNMR, IR, MS, Safety Data Sheet (SDS/MSDS) etc.
仓储与运输
冷冻或冷藏保存,避免强光与高温。
参考文献
[1]. Shen T, et al. Cafestol, a coffee-specific diterpene, is a novel extracellular signal-regulated kinase inhibitor with AP-1-targeted inhibition of prostaglandin E2 production in lipopolysaccharide-activated macrophages. Biol Pharm Bull. 2010;33(1):128-32.
[2]. Wang S, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71.
[3]. Feng Y, et al. Cafestol inhibits colon cancer cell proliferation and tumor growth in xenograft mice by activating LKB1/AMPK/ULK1-dependent autophagy. J Nutr Biochem. 2024 Jul;129:109623.
[4]. Mellbye FB, et al. Cafestol, a Bioactive Substance in Coffee, Has Antidiabetic Properties in KKAy Mice. J Nat Prod. 2017 Aug 25;80(8):2353-2359.
[2]. Wang S, et al. Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2012 May 11;421(3):567-71.
[3]. Feng Y, et al. Cafestol inhibits colon cancer cell proliferation and tumor growth in xenograft mice by activating LKB1/AMPK/ULK1-dependent autophagy. J Nutr Biochem. 2024 Jul;129:109623.
[4]. Mellbye FB, et al. Cafestol, a Bioactive Substance in Coffee, Has Antidiabetic Properties in KKAy Mice. J Nat Prod. 2017 Aug 25;80(8):2353-2359.
声明
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*本产品不用于诊断、治疗、治愈或预防任何疾病,仅供科研研究使用。