Fusicoccin from Fusicoccum amygdali
APC-1808
Fusicoccin from Fusicoccum amygdali
Cat. No.
APC-1808
CAS No.
20108-30-9
MF
C36H56O12
MW
680.82
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Description
Documents
Storage and Shipping
References
Product Name
CAS No.
20108-30-9
MF
C36H56O12
MW
680.82
Specification
85%
Description
Fusicoccin (Fusicoccin A), a fungal pytotoxin, is a stabilizer of specific 14-3-3 protein-protein interactions. Fusicoccin sabilizes H+-ATPase/14-3-3 cmplex in pants, maintaining the enzyme in activated state. Fusicoccin also stabilizes 14-3-3 protein interactions with binding partners containing a C-terminal 14-3-3 recognition motif (a mode 3 motif), such as ERα, GPIbα, TASK3, CTFR, and p53. Fusicoccin induces apoptosis in cancer cells and has anticancer activity Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g Availability: In stock
Documents
Certificate of Analysis (CoA) with HPLC, 1HNMR, 13CNMR, IR and MS etc. Safety Data Sheet (SDS/MSDS)
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Storage and Shipping
Store in a cool and dry place, avoid strong light and high temperature
References
[1].Ballio A, Brufani M, Casinovi CG, Cerrini S, Fedeli W, Pellicciari R, Santurbano B, Vaciago A. The structure of fusicoccin A. Experientia. 1968;24(6):631-634.
[2].Ballio A, Castellano S, Cerrini S, Evidente A, Randazzo G, Segre AL. ¹H NMR conformational study of fusicoccin and related compounds: molecular conformation and biological activity. Phytochemistry. 1991;30(1):137-145.
[3].Marra M, Camoni L, Visconti S, Fiorillo A, Evidente A. The Surprising Story of Fusicoccin: A Wilt-Inducing Phytotoxin, a Tool in Plant Physiology and a 14-3-3-Targeted Drug. Biomolecules. 2021;11(9):1393.
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