服务支持 需要帮助？我们经验深厚的专家团队，随时为您提供全力支持。
AKA-317
辛可宁
产品编号
AKA-317
CAS号码
118-10-5
分子式
C19H22N2O
分子量
294.4
先进设备与成熟工艺
规模化生产
质量稳定
可支持定制
基本信息
产品描述
文件支持
仓储与运输
参考文献
中文名称
辛可宁
英文名称
(+)-Cinchonine
CAS号码
118-10-5
分子式
C19H22N2O
分子量
294.4
规格
98%
Research Area
Cinchonine, a quinoline-type alkaloid extracted from cinchona bark, primarily exhibits antimalarial and antipyretic biological activities, with recent studies indicating its ability to promote tumor cell apoptosis. As both an antimalarial agent and a catalyst in asymmetric synthesis, this compound is widely utilized in pharmaceuticals and organic synthesis, often employed in the preparation of antitumor drugs.
产品描述
辛可宁是一种天然化合物。 包装: 1kg/袋; 25kg/桶或按需分装 供货情况: 现货供应
文件支持
仓储与运输
密封，避光，2-8℃冷藏保存
参考文献
[1]. Qi Y, et al. Cinchonine induces apoptosis of HeLa and A549 cells through targeting TRAF6. Journal of Experimental & Clinical Cancer Research. 2017 Feb 23;36(1):35.
[2]. Jin ZL, et al. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Experimental and Therapeutic Medicine. 2018 Jun;15(6):5046-5050.
[3]. Wang H, et al. Cinchonine exerts anti-tumor and immunotherapy sensitizing effects in lung cancer by impairing autophagic-lysosomal degradation. Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie. 2023 Aug;164:114980.
[4]. Jung SA, et al. Cinchonine Prevents High-Fat-Diet-Induced Obesity through Downregulation of Adipogenesis and Adipose Inflammation. PPAR Research. 2012;2012:541204.
[5]. Jo YJ, et al. Cinchonine inhibits osteoclast differentiation by regulating TAK1 and AKT, and promotes osteogenesis. Journal of Cellular Physiology. 2021 Mar;236(3):1854-1865.
[6]. Shah BH, et al. The inhibitory effect of cinchonine on human platelet aggregation due to blockade of calcium influx. Biochemical Pharmacology. 1998 Oct 15;56(8):955-60.
声明
本产品仅限科学研究或药证申报使用，我们不向个人提供产品和服务。请严格遵守法律法规及承诺用途，不得用于其他任何目的。
相关产品
AKA-370
氧化苦参碱
CAS号码:16837-52-8
分子式:C15H24N2O2
AKA-369
苦参碱
CAS号码:519-02-8
分子式:C15H24N2O
AKA-372
Dipexion™ (4S)-3-[(2S)-2-[[芴甲氧羰基]氨基]-3-甲基-1-氧代丁基]-2,2-二甲基-4-恶唑烷羧酸
CAS号码:186023-49-4
分子式:C26H30N2O6
AKA-371
Dipexion™ (4S)-3-[2-[[芴甲氧羰基]氨基]乙酰基]-2,2-二甲基-4-恶唑烷羧酸
CAS号码:1095952-22-9
分子式:C23H24N2O6
AKA-368
Dipexion™ (4S,5R)-3-[(2S)-6-[[叔丁氧羰基]氨基]-2-[[芴甲氧羰基]氨基]-1-氧代己基]-2,2,5-三甲基-4-恶唑烷羧酸
CAS号码:911838-56-7
分子式:C33H43N3O8
AKA-367
Dipexion™ (4S)-3-[(2S)-2-[[芴甲氧羰基]氨基]-4-甲基-1-氧代戊基]-2,2-二甲基-4-恶唑烷羧酸
CAS号码:339531-50-9
分子式:C27H32N2O6
AKA-366
Dipexion™ (4S,5R)-3-[(2S)-3-(叔丁氧基)-2-[[芴甲氧羰基]氨基]-1-氧代丙基]-2,2,5-三甲基-4-恶唑烷羧酸
CAS号码:1266350-99-5
分子式:C29H36N2O7
AKA-365
Dipexion™ (4S,5R)-3-((S)-2-((((9H-芴-9-基)甲氧基)羰基)氨基)-5-(叔丁氧基)-5-氧代戊酰基)-2,2,5-三甲基恶唑烷-4-羧酸
CAS号码:957780-56-2
分子式:C31H38N2O8
AKA-364
Dipexion™ (4S)-3-[(2S)-6-[[叔丁氧羰基]氨基]-2-[[芴甲氧羰基]氨基]-1-氧代己基]-2,2-二甲基-4-恶唑烷羧酸
CAS号码:957780-54-0
分子式:C32H41N3O8
AKA-363
Dipexion™ (4S)-3-[(2S,3R)-3-(叔丁氧基)-2-[[芴甲氧羰基]氨基]-1-氧代丁基]-2,2-二甲基-4-恶唑烷羧酸
CAS号码:1425938-63-1
分子式:C29H36N2O7
*本产品不用于诊断、治疗、治愈或预防任何疾病，仅供科研研究使用。
