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AKA-304
6,7-二羟基香豆素
产品编号
AKA-304
CAS号码
305-01-1
分子式
C9H6O4
分子量
178.14
先进设备与成熟工艺
规模化生产
质量稳定
可支持定制
基本信息
产品描述
文件支持
仓储与运输
参考文献
中文名称
6,7-二羟基香豆素
英文名称
Esculetin
CAS号码
305-01-1
分子式
C9H6O4
分子量
178.14
规格
98%
Research Area
6,7-Dihydroxycoumarin (also known as esculetin or aesculetin) is an important pharmaceutical intermediate, primarily used for the synthesis of the antiasthmatic drug dimethoxycoumarin. It possesses notable pharmacological activities, including antibacterial, antiasthmatic, expectorant, and antitussive effects, particularly demonstrating inhibitory activity against Shigella species. Clinically, it is commonly used in the treatment of acute bacillary dysentery and chronic bronchitis.
产品描述
6,7-二羟基香豆素是一种活性成分。 包装: 1kg/袋; 25kg/桶或按需分装 供货情况: 现货供应
文件支持
仓储与运输
密封，避光，2-8℃冷藏保存
参考文献
[1]. Xie C, et al. Esculetin regulates the phenotype switching of airway smooth muscle cells. Phytotherapy Research. 2019 Aug 21.
[2]. Arora R, et al. Esculetin induces antiproliferative and apoptotic response in pancreatic cancer cells by directly binding to KEAP1. Molecular Cancer. 2016 Oct 18;15(1):64.
[3]. Chen Y, et al. Esculetin Ameliorates Psoriasis-Like Skin Disease in Mice by Inducing CD4+Foxp3+ Regulatory T Cells. Frontiers in Immunology. 2018 Sep 12;9:2092.
[4]. Kim WK, et al. Esculetin suppresses tumor growth and metastasis by targeting Axin2/E-cadherin axis in colorectal cancer. Biochemical Pharmacology. 2018 Jun;152:71-83.
[5]. Martín-Aragón S, et al. Age-dependent effects of esculetin on mood-related behavior and cognition from stressed mice are associated with restoring brain antioxidant status. Progress in Neuro-psychopharmacology & Biological Psychiatry. 2016 Feb 4;65:1-16.
声明
本产品仅限科学研究或药证申报使用，我们不向个人提供产品和服务。请严格遵守法律法规及承诺用途，不得用于其他任何目的。
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*本产品不用于诊断、治疗、治愈或预防任何疾病，仅供科研研究使用。
