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AKA-354
Rimegepant Sulfate
Cat. No.
AKA-354
CAS No.
1374024-48-2
MF
C56H64F4N12O13S
MW
1221.2
Rimegepant sulfate is a competitive antagonist of the calcitonin gene-related peptide (CGRP) receptor.
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Description
Documents
Storage and Shipping
References
Product Name
Rimegepant Sulfate
CAS No.
1374024-48-2
MF
C56H64F4N12O13S
MW
1221.2
Specification
98%-102%
Research Area
Antimigraine agents
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
Description
Rimegepant sulfate is a competitive antagonist of the calcitonin gene-related peptide (CGRP) receptor. Packing: 1kg/bag; 25kg/drum or as request Availability: In stock
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Guanglin Luo, et al. Discovery of (5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate (BMS-927711): An Oral Calcitonin Gene-Related Peptide (CGRP) Antagonist in Clinical Trials for Treating Migraine. Journal of Medicinal Chemistry. 02 Nov 2012
[2]. Nekomoto A, et al. Feasibility of administration of calcitonin gene-related peptide receptor antagonist on attenuation of pain and progression in osteoarthritis. Sci Rep. 2023;13(1):15354. Published 2023 Sep 16.
[3]. Pistolesi A, et al. Biodistribution of atogepant and rimegepant in mouse peripheral and central structures of relevance to migraine pathogenesis. Cephalalgia. 2025;45(11):3331024251378713.
[4]. Mulder IA, et al. Anti-migraine Calcitonin Gene-Related Peptide Receptor Antagonists Worsen Cerebral Ischemic Outcome in Mice. Ann Neurol. 2020;88(4):771-784.
[5]. Ike E, et al. Calcitonin Gene-Related peptide receptor antagonist suppresses allergic asthma responses via downregulation of group 2 innate lymphoid cells in mice. Int Immunopharmacol. 2023;122:110608.
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