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AKA-316
Quinidine
Cat. No.
AKA-316
CAS No.
56-54-2
MF
C20H24N2O2
MW
324.4
Quinidine is a potent, active, selective cytochrome P450db inhibitor.
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Description
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References
Product Name
Quinidine
CAS No.
56-54-2
MF
C20H24N2O2
MW
324.4
Specification
98%
Research Area
Quinidine is a natural alkaloid primarily employed as an antiarrhythmic agent. In the pharmaceutical industry, it also serves as a key intermediate in the synthesis of other chiral drugs or derivatives, and is utilized as a reference standard in ion channel research.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
Description
Quinidine is a potent, active, selective cytochrome P450db inhibitor. Packing: 1kg/bag; 25kg/drum or as request Availability: In stock
Documents
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Storage and Shipping
Store sealed, protected from light, at 2-8°C.
References
[1]. Sang-Yun Lee, et al. Hydrocinchonine, cinchonine, and quinidine potentiate paclitaxel-induced cytotoxicity and apoptosis via multidrug resistance reversal in MESSA/DX5 uterine sarcoma cells. Environmental Toxicology. 2011 Aug;26(4):424-31.
[2]. Hassan Jamali, et al. Effect of dextromethorphan/quinidine on pentylenetetrazole-induced clonic and tonic seizure thresholds in mice. Neuroscience Letters. 2020 Jun 11;729:134988.
[3]. Moody DE, et al. Quinidine inhibits in vivo metabolism of amphetamine in rats: impact upon correlation between GC/MS and immunoassay findings in rat urine. Journal of Analytical Toxicology. 1990 Sep-Oct;14(5):311-7.
[4]. Kehl SJ, et al. Quinidine-induced inhibition of the fast transient outward K+ current in rat melanotrophs. British Journal of Pharmacology. 1991 Jul;103(3):1807-13.
[5]. Roden DM, et al. Class I antiarrhythmic agents: quinidine, procainamide and N-acetylprocainamide, disopyramide.
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