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AKA-303
Arecoline Hydrobromide
Cat. No.
AKA-303
CAS No.
300-08-3
MF
C8H13NO2.HBr
MW
236.11
Arecoline hydrobromide, a naturally brain-penetrant and active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor.
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Description
Documents
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References
Product Name
Arecoline Hydrobromide
CAS No.
300-08-3
MF
C8H13NO2.HBr
MW
236.11
Specification
98%
Research Area
Arecoline hydrobromide (CAS 300-08-3), the hydrobromide salt of an alkaloid extracted from the seeds of the betel nut palm (Areca catechu), is a white to off-white crystalline powder. It acts as a cholinergic receptor agonist with parasympathomimetic effects and is clinically used primarily as an anthelmintic (e.g., against tapeworms) and in the treatment of glaucoma. Additionally, it has been investigated for applications such as an antiarrhythmic agent and a pre-exercise supplement.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
Description
Arecoline hydrobromide, a naturally brain-penetrant and active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Packing: 1kg/bag; 25kg/drum or as request
Documents
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Storage and Shipping
Store in a tightly sealed container, protected from light, refrigerated or frozen.
References
[1]. Thangjam GS, et al. Regulation of oxidative-stress responsive genes by arecoline in human keratinocytes. Journal of Periodontal Research. 2009;44(5):673-82.
[2]. Liu YJ, et al. Anti-inflammatory effects of arecoline in a mouse model of collagen-induced arthritis. Pharmaceutical Biology. 2016;54(11):2753-2760.
[3]. Volgin AD, et al. DARK Classics in Chemical Neuroscience: Arecoline. ACS Chemical Neuroscience. 2019;10(5):2176-2185.
[4]. Kuo TM, et al. Arecoline induces TGF-β1 production and tissue transglutaminase expression in oral keratinocytes. Journal of Biomedical Science. 2014;21(1):93.
[5]. Chen QY, et al. Arecoline aggravates acute ischemic stroke by promoting neuroinflammation via NF-κB signaling. Molecular Brain. 2024;17(1):39.
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