Technical Service Need help? Our team of experienced experts is here for you with full support.
AKA-302
4'-Demethylepipodophyllotoxin
Cat. No.
AKA-302
CAS No.
6559-91-7
MF
C21H20O8
MW
400.38
4'-Demethylepipodophyllotoxin is an intermediate compound that inhibits microtubule assembly.
Advanced Equipments & Extensive Production Expertise
Commercial Manufacturing
Stable Quality
Customization Supporting
Technical Service 
86-28-85159085 
info@aktin.com Technical Data
Description
Documents
Storage and Shipping
References
Product Name
4'-Demethylepipodophyllotoxin
CAS No.
6559-91-7
MF
C21H20O8
MW
400.38
Specification
98%
Research Area
4'-Demethylepipodophyllotoxin (4'-DMEP) is a white crystalline lignan natural product derived from podophyllotoxin. It serves as a critical pharmaceutical intermediate for the synthesis of potent antitumor drugs such as etoposide and teniposide, exhibiting notable biological activities including inhibition of microtubule assembly, antitumor, and antiviral effects.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
Description
4'-Demethylepipodophyllotoxin is an intermediate compound that inhibits microtubule assembly. Packing: 1kg/bag; 25kg/drum or as request Availability: In stock
Documents
Can't find the right version? Our team of experienced experts is here for you with full support.Contact Us
Storage and Shipping
Store sealed, protected from light, at 2-8°C.
References
[1]. Tang YJ, Zhao W, Li HM. Novel tandem biotransformation process for the biosynthesis of a novel compound, 4-(2,3,5,6-tetramethylpyrazine-1)-4'-demethylepipodophyllotoxin. Applied and Environmental Microbiology. 2011;77(9):3023-34.
[2]. Dhawan D, et al. Preclinical evaluation of 4'-demethylepipodophyllotoxin analogue as a topoisomerase II inhibitor. Carcinogenesis. 1999;20(6):997-1003.
[3]. Xiang Zhou, et al. Facile synthesis of a series of 4'-demethylepipodophyllotoxin (DMEP) derivatives. Industrial Crops and Products. 2021;174:114182.
Related Products
* Some statements have not been evaluated by national authorities. * Some products are not intended to diagnose, treat, cure, or prevent any disease. * For literature supporting, please contact us directly.
