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AKA-290
Theophylline
Cat. No.
AKA-290
CAS No.
58-55-9
MF
C7H8N4O2
MW
80.164
Theophylline is a potent phosphodiesterase (PDE) inhibitor, adenosine receptor antagonist and histone deacetylase (HDAC) activator.
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Description
Documents
Storage and Shipping
References
Product Name
Theophylline
CAS No.
58-55-9
MF
C7H8N4O2
MW
80.164
Specification
99%
Research Area
Intermediate
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
Description
Theophylline is a potent phosphodiesterase (PDE) inhibitor, adenosine receptor antagonist and histone deacetylase (HDAC) activator. Packing: 1kg/bag; 25kg/drum or as request
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Rabe KF, et al. Theophylline and selective PDE inhibitors as bronchodilators and smooth muscle relaxants. The European Respiratory Journal. 1995 Apr;8(4):637-42.
[2]. Németh ZH, et al. Amrinone and theophylline differentially regulate cytokine and nitric oxide production in endotoxemic mice. Shock. 1997 May;7(5):371-5.
[3]. Ichiyama T, et al. Theophylline inhibits NF-kappa B activation and I kappa B alpha degradation in human pulmonary epithelial cells. Naunyn-Schmiedeberg's Archives of Pharmacology. 2001 Dec;364(6):558-61.
[4]. Ito K, et al. A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. Proceedings of the National Academy of Sciences of the United States of America. 2002 Jun 25;99(13):8921-6.
[5]. Barnes PJ. Theophylline. American Journal of Respiratory and Critical Care Medicine. 2013 Oct 15;188(8):901-6.
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