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AKA-252
Baccatin III
Cat. No.
AKA-252
CAS No.
27548-93-2
MF
C31H38O11
MW
586.62682
Baccatin III is an active, selective inhibitor of TGF-β1 signaling pathway and myeloid-derived suppressor cell (MDSC) activation and is an inactive precursor for the synthesis of Paclitaxel.
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Description
Documents
Storage and Shipping
References
Product Name
Baccatin III
CAS No.
27548-93-2
MF
C31H38O11
MW
586.62682
Specification
98%
Research Area
Intermediate
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
Description
Baccatin III is an active, selective inhibitor of TGF-β1 signaling pathway and myeloid-derived suppressor cell (MDSC) activation and is an inactive precursor for the synthesis of Paclitaxel. Packing: 1kg/bag; 25kg/drum or as request Availability: In Stock
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Lee YH, et al. Baccatin III, a precursor for the semisynthesis of paclitaxel, inhibits the accumulation and suppressive activity of myeloid-derived suppressor cells in tumor-bearing mice. International Immunopharmacology. 2014 Aug;21(2):487-93.
[2]. Nie Y, et al. Baccatin III ameliorates bleomycin-induced pulmonary fibrosis via suppression of TGF-β1 production and TGF-β1-induced fibroblast differentiation. International Immunopharmacology. 2019 Sep;74:105696.
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