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AKA-248
Harmine
Cat. No.
AKA-248
CAS No.
442-51-3
MF
C13H12N2O
MW
212.25
Harmine is a natural dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor; Harmine has a high affinity for 5-HT2A serotonin receptor.
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Product Name
Harmine
CAS No.
442-51-3
MF
C13H12N2O
MW
212.25
Specification
98%
Research Area
Intermediate
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
Description
Harmine is a natural dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor; Harmine has a high affinity for 5-HT2A serotonin receptor. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g, 1kg Availability: research and bulk quantity
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Glennon RA, et al. Binding of beta-carbolines and related agents at serotonin (5-HT(2) and 5-HT(1A)), dopamine (D(2)) and benzodiazepine receptors. Drug and Alcohol Dependence. 2000 Aug 1;60(2):121-32.
[2]. Neumann F, et al. DYRK1A inhibition and cognitive rescue in a Down syndrome mouse model are induced by new fluoro-DANDY derivatives. Scientific Reports. 2018 Feb 12;8(1):2859.
[3]. Zhang L, et al. Harmine suppresses homologous recombination repair and inhibits proliferation of hepatoma cells. Cancer Biology & Therapy. 2015;16(11):1585-92.
[4]. Zhong Z, et al. Treatment with harmine ameliorates functional impairment and neuronal death following traumatic brain injury. Molecular Medicine Reports. 2015 Dec;12(6):7985-91.
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