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AKA-188
Maytansine
Cat. No.
AKA-188
CAS No.
35846-53-8
MF
C34H46ClN3O10
MW
692.2
Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest at subnanomolar concentrations.
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Product Name
Maytansine
CAS No.
35846-53-8
MF
C34H46ClN3O10
MW
692.2
Specification
98%
Research Area
Intermediate
Description
Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest at subnanomolar concentrations. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g, 1kg Availability: Under Development (current pilot scale, validation production in 3-4 month, DMF filing in 12 month)
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Lopus M, et al. Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules. Molecular Cancer Therapeutics. 2010;9(10):2689-2699.
[2]. Remillard S, et al. Antimitotic activity of the potent tumor inhibitor maytansine. Science. 1975;189(4207):1002-1005.
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