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AKA-184
Tabersonine Hydrochloride
Cat. No.
AKA-184
CAS No.
29479-00-3
MF
C21H25ClN2O2
MW
372.9
Tabersonine hydrochloride is a selective, active NLRP3 inhibitor that directly binds to the NACHT domain of NLRP3, inhibiting its ATPase activity and oligomerization.
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Description
Documents
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References
Product Name
Tabersonine Hydrochloride
CAS No.
29479-00-3
MF
C21H25ClN2O2
MW
372.9
Specification
97%
Research Area
Intermediate
Description
Tabersonine hydrochloride is a selective, active NLRP3 inhibitor that directly binds to the NACHT domain of NLRP3, inhibiting its ATPase activity and oligomerization. Packing: 1kg/bag; 25kg/drum or as request Availability: In Stock
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Zhou Z, et al. Tabersonine, a natural NLRP3 inhibitor, suppresses inflammasome activation in macrophages and attenuates NLRP3-driven diseases in mice. Acta Pharmacologica Sinica. 2023;44(5):1029-1037.
[2]. He Y, et al. Tabersonine induces apoptosis via mitochondrial pathway and death receptor pathway in hepatocellular carcinoma cells. Phytotherapy Research. 2023;37(6):2353-2363.
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