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AKA-147
Sophocarpine
Cat. No.
AKA-147
CAS No.
6483-15-4
MF
C15H22N2O
MW
246.354
Sophocarpine is a PTEN activator and an inhibitor of PI3K/Akt, MEK/ERK and NF-κB signaling pathways.
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Description
Documents
Storage and Shipping
References
Product Name
Sophocarpine
CAS No.
6483-15-4
MF
C15H22N2O
MW
246.354
Specification
98%
Research Area
Intermediate
Description
Sophocarpine is a PTEN activator and an inhibitor of PI3K/Akt, MEK/ERK and NF-κB signaling pathways. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g, 1kg Availability: In stock
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Xing S, et al. Sophocarpine inhibits the progression of glioblastoma via PTEN/PI3K/Akt signaling pathway. American Journal of Cancer Research. 2024 Aug 25;14(8):3757-3772.
[2]. Wang Q, et al. Sophocarpine Inhibits Tumorgenesis of Colorectal Cancer via Downregulation of MEK/ERK/VEGF Pathway. Biological & Pharmaceutical Bulletin. 2019 Nov 1;42(11):1830-1838.
[3]. Gao Y, et al. Anti-inflammatory effects of sophocarpine in LPS-induced RAW 264.7 cells via NF-κB and MAPKs signaling pathways. Toxicology in Vitro. 2012 Feb;26(1):1-6.
[4]. Zhang HJ, et al. Sophocarpine alleviates doxorubicin-induced heart injury by suppressing oxidative stress and apoptosis. Scientific Reports. 2024 Jan 3;14(1):428.
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