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AKA-131
Lithocholic acid
Cat. No.
AKA-131
CAS No.
434-13-9
MF
C24H40O3
MW
376.5726
Lithocholic acid is a toxic secondary bile acid that can promote intrahepatic cholestasis.
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References
Product Name
Lithocholic acid
CAS No.
434-13-9
MF
C24H40O3
MW
376.5726
Specification
98%
Research Area
Intermediate
Description
Lithocholic acid is a toxic secondary bile acid that can promote intrahepatic cholestasis. Packing: 1kg/bag; 25kg/drum or as request Availability: In Stock
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Jenkins, D.J., et al., Effect on blood lipids of very high intakes of fiber in diets low in saturated fat and cholesterol. N Engl J Med, 1993. 329(1): p. 21-6.
[2]. Yang R, et al. Metabolomic analysis of cholestatic liver damage in mice. Food and Chemical Toxicology. 2018 Jul 14;120:253-260.
[3]. Goldberg, A.A., et al., Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells. Oncotarget, 2011. 2(10): p. 761-82.
[4]. Matsubara, T., et al., TGF-beta-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury. J Lipid Res, 2012. 53(12): p. 2698-707.
[5]. Yu J, et al. Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity. The Journal of Biological Chemistry. 2002 Aug 30;277(35):31441-7.
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