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AKA-126
(S)-10-Hydroxycamptothecin
Cat. No.
AKA-126
CAS No.
19685-09-7
MF
C20H16N2O5
MW
364.35
(S)-10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor.
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Documents
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References
Product Name
(S)-10-Hydroxycamptothecin
CAS No.
19685-09-7
MF
C20H16N2O5
MW
364.35
Specification
98%
Research Area
Intermediate
Description
(S)-10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor. Packing: 1kg/bag; 25kg/drum or as request Availability: In Stock
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Liu M, et al. Intracellular delivery of 10-hydroxycamptothecin with targeted nanostructured lipid carriers against multidrug resistance. Journal of Drug Targeting. 2016;24(5):433-440.
[2]. Yu P, et al. Synthesis and preliminary anticancer evaluation of 10-hydroxycamptothecin analogs. Biological & Pharmaceutical Bulletin. 2012;35(8):1295-1299.
[3]. Zhang XW, et al. Differentiation-inducing action of 10-hydroxycamptothecin on human hepatoma Hep G2 cells. Acta Pharmacologica Sinica. 2000;21(4):364-368.
[4]. Zhang XW, et al. Differential regulation of P53, c-Myc, Bcl-2, Bax and AFP protein expression, and caspase activity during 10-hydroxycamptothecin-induced apoptosis in Hep G2 cells. Anti-cancer Drugs. 2000;11(9):747-756.
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