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AKA-49
Ertugliflozin
Cat. No.
AKA-49
CAS No.
1210344-57-2
MF
C22H25ClO7
MW
436.9
Ertugliflozin is a potent, selective and active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).
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Description
Documents
Storage and Shipping
References
Product Name
Ertugliflozin
CAS No.
1210344-57-2
MF
C22H25ClO7
MW
436.9
Specification
98%
Research Area
Intermediate
Description
Ertugliflozin is a potent, selective and active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2). Packing: 1kg/bag; 25kg/drum or as request Availability: In Stock
Documents
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Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Mascitti V, et al. Discovery of a clinical candidate from the structurally unique dioxa-bicyclo[3.2.1]octane class of sodium-dependent glucose cotransporter 2 inhibitors. Journal of Medicinal Chemistry. 2011 Apr 28;54(8):2952-60. PMID: 21449606
[2]. Miao Z, et al. Pharmacokinetics, metabolism, and excretion of the antidiabetic agent ertugliflozin (PF-04971729) in healthy male subjects. Drug Metabolism and Disposition. 2013 Feb;41(2):445-56. PMID: 23169609
[3]. Kalgutkar AS, et al. Preclinical species and human disposition of PF-04971729, a selective inhibitor of the sodium-dependent glucose cotransporter 2 and clinical candidate for the treatment of type 2 diabetes mellitus. Drug Metabolism and Disposition. 2011 Sep;39(9):1609-19. PMID: 21690265
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